Angiogenesis and portal-systemic collaterals in portal hypertension
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چکیده
منابع مشابه
Angiogenesis and portal-systemic collaterals in portal hypertension.
In patients with advanced liver disease with portal hypertension, portal-systemic collaterals contribute to circulatory disturbance, gastrointestinal hemorrhage, hepatic encephalopathy, ascites, hepatopulmonary syndrome and portopulmonary hypertension. Angiogenesis has a pivotal role in the formation of portal-systemic shunts. Recent research has defined many of the mediators and mechanisms inv...
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223 Chronic liver diseases or liver injuries commonly result in increased intrahepatic resistance and subsequently lead to portal hypertension. Portal hypertension is associated with 2 distinct pathophysiologic features: hyper-dynamic circulation and formation of portal-systemic collaterals. 1 Hyperdynamic circulation is characterized by increased splanchnic blood flow, cardiac output, decrease...
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We report a case of systemic mastocytosis (SM) presenting as ascites and portal hypertension. The haematological picture at presentation was suggestive of chronic myelomonocytic leukaemia. Initial difficulties in making a diagnosis of SM were encountered as the cutaneous signs were atypical. The correct diagnosis was established only after tissue sections were appropriately stained for mast cel...
متن کاملInvolvement of constitutive nitric oxide synthase in the portal-systemic collaterals of portal hypertensive rats.
BACKGROUND Recent studies have shown that endothelial nitric oxide (NO) is involved in modulating the vascular response to vasoconstrictors in portal-systemic collaterals of portal hypertensive rats. This study investigated which isoform of NO synthase is involved in the collateral circulation of portal hypertensive rats. METHODS The relaxation response to acetylcholine (10(-8) M, 10(-7) M an...
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A 43-year-old woman with a huge portal-systemic shunt accompanied by myxedema showed slow speech and behavior. Several imaging studies revealed a bold portal-systemic shunt from the splenic vein to the left renal vein. In addition, hypothyroidism caused by chronic thyroiditis was diagnosed, and synthesized thyroxine replacement was effective for the symptoms. However, the serum ammonia and indo...
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ژورنال
عنوان ژورنال: Annals of Hepatology
سال: 2016
ISSN: 1665-2681
DOI: 10.5604/16652681.1198799